In a groundbreaking development at ETH Zurich, scientists have invented a protein gel with the potential to neutralize alcohol before it reaches an individual’s bloodstream, a step towards averting millions of fatalities due to excessive alcohol consumption. The gel, which proved effective in reducing blood alcohol levels by up to 50 percent in mice and safeguarding their bodies from harm, functions by converting alcohol into harmless acetic acid just before it gets metabolized by the body.
Alcohol bypasses normal digestive processes, entering the bloodstream directly through the stomach and intestines. Subsequently, it rapidly affects all body organs. This alcohol is converted into toxic acetaldehyde — which eventually breaks down into harmless acetate — posing potential bodily harm.
Focusing on this harmful acetaldehyde stage, the researchers developed a gel that remedies this by directly moving alcohol to its harmless acetate form. The gel accelerates the alcohol breakdown process from the liver to the digestive tract, eliminating the toxic acetaldehyde intermediate stage.
While initial trials on mice have succeeded, additional testing must occur before the product can be approved for use in humans. As the scientists noted, it remains healthier to avoid alcohol. Yet, the gel provides a promising solution for those seeking moderation rather than abstinence, potentially negating alcohol’s adverse impacts. The research team has filed for a patent and aims to progress with clinical trials to eventually release the product for public use, marking a significant advancement in harm-reduction strategies related to alcohol consumption.