❓WHAT HAPPENED: A study published in August suggested that acetaminophen (paracetamol) use during pregnancy may increase the risk of autism and ADHD in children. Acetaminophen is commonly sold under the brand name Tylenol in the U.S.
👤WHO WAS INVOLVED: Harvard T.H. Chan School of Public Health and Icahn School of Medicine at Mount Sinai led the research.
📍WHEN & WHERE: Published on August 14, 2025, in BMC Environmental Health.
💬KEY QUOTE: “That association is strongest when acetaminophen is taken for four weeks or longer.” – Andrea Baccarelli
🎯IMPACT: The U.S. Food and Drug Administration (FDA) plans to advise clinicians on cautious use of acetaminophen during pregnancy.
An August study brought attention to the potential risks associated with the use of acetaminophen (paracetamol) during pregnancy. The research, published in BMC Environmental Health, indicates that exposure to this common medication, usually sold under the brand name Tylenol in the U.S., might increase the likelihood of autism and ADHD in children.
The study was spearheaded by the Icahn School of Medicine at Mount Sinai, with contributions from Harvard T.H. Chan School of Public Health. Researchers reviewed 46 studies from around the world, employing the Navigation Guide Systematic Review methodology to find evidence of a connection between acetaminophen use during pregnancy and an increased incidence of neurodevelopmental disorders (NDDs).
The U.S. Food and Drug Administration (FDA) is preparing to issue guidance to clinicians, following discussions between Andrea Baccarelli, a senior author on the study and professor at Harvard, and Health and Human Services Secretary Robert F. Kennedy Jr.
Baccarelli, who has served as an expert witness in related legal cases, stated, “Further research is needed to confirm the association and determine causality, but based on existing evidence, I believe that caution about acetaminophen use during pregnancy—especially heavy or prolonged use—is warranted.”
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